Acromegaly (say "ack-roh-MEH-guh-lee") is a condition in which the body makes too much growth hormone. This causes abnormal growth of bones and tissues. It is noticed mostly in the hands and feet. It can also affect internal organs, such as the heart. The condition also can cause changes in the face. For example, the brow and lower jaw can grow and stick out, and the nasal bone can get bigger. In most cases, these changes happen slowly over many years.
People with the condition may have a greater risk of certain diseases such as diabetes, high blood pressure, and arthritis. And they may have other problems such as sleep apnea and headaches. This condition can be painful. This is because the bones may keep growing after they have reached their adult size.
Acromegaly is often caused by a tumor of the pituitary gland, which is where growth hormone is made. But the tumor isn't cancer. It can be treated with medicine, surgery, radiation treatment, or some combination of these. Rarely, a tumor in a different part of the body, such as in the pancreas gland, can cause the pituitary gland to make too much growth hormone. This also can lead to acromegaly. Treatment may stop some abnormal growth, but bones don't go back to normal after the treatment.
Acromegaly is a hormonal disorder in which the pituitary gland produces too much growth hormone. This disorder causes abnormal enlargement of bones and tissues, noticeably in the hands and feet, which occurs gradually over several years.
Enlarged bones in the nose and mouth may cause a large tongue and widely spaced teeth and may lead to sleep apnea. Bone and cartilage growth may lead to arthritis. People with acromegaly can also develop diabetes, high blood pressure, and other problems.
The excess production of growth hormone usually is caused by a tumor of the pituitary gland. Acromegaly is usually treated with medicine, surgery, or radiation treatment to the tumor.
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