Clostridioides difficile toxins test

The test is done to see if diarrhea that won't go away was caused by Clostridioides difficile (C. diff) toxins.

Stool samples can be collected at home. Or you may need to go to your doctor's office, a medical clinic, or the hospital. If you collect the sample at home, you may be given a special container.

You may need to collect more than one sample. Follow the same steps for each sample.

To collect the sample:

• Urinate before you collect the stool. That way, you won't get any urine in the stool sample. Do not urinate while you pass the stool.
• Wash your hands with soap and clean, running water before and after you collect the sample. Do not use an alcohol-based hand sanitizer instead of washing your hands. Sanitizer will not kill C. diff.
• Put on gloves before handling your stool. Stool can contain germs that spread infection. Wash your hands before you put on your gloves and after you take them off.
• Pass stool (but no urine) into a dry container. You may be given a plastic basin that you can place under the toilet seat to catch the stool.
  • For diarrhea, a large plastic bag taped to the toilet seat may make the collection process easier. The bag is then placed in a plastic container.
  • Do not collect the sample from the toilet bowl.
  • Do not mix toilet paper, water, or soap with the sample.
• Place the lid on the container. Label it with your name, your doctor's name, and the date the stool was collected.

Take the sample to your doctor's office or the lab as soon as you can. You may need to take your sample to the lab within a certain time, usually within 30 minutes or less of collecting it. Tell your doctor if you think you may have trouble getting the sample to the lab on time.

Samples from babies and young children may be taken from diapers (if the stool does not have urine mixed with it). Or a narrow tube may be put into the baby's rectum while you hold the baby on your lap.

Tell your doctor if you have recently taken antibiotics.

There are several types of tests for this toxin. Depending on the test used, results may take several hours or a day or two.