Corticobasal syndrome (CBS) is a rare disorder that, over time, causes many areas of the brain to shrink. The first symptoms may be problems with thinking. But CBS also can cause changes in the way a person acts, speaks, or moves. Movement symptoms often start in one arm or leg. Some symptoms of CBS are similar to Parkinson's disease, but they may come later as CBS progresses. These may include tremor, stiffness, and problems with balance.
Problems with understanding spoken or written language may develop. A problem called "alien limb" can occur in which the person has trouble controlling the movement of a limb.
Although there is no cure for CBS, medicines can treat symptoms.
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