What is multiple sclerosis?

Multiple Sclerosis

Multiple sclerosis (MS): Overview

Multiple sclerosis (MS) is a disease that affects the central nervous system—the brain and spinal cord. It also affects the nerves to the eyes. Symptoms vary from person to person. It can cause problems with muscle strength, vision, balance, mood, and thinking. And it may cause fatigue, pain, muscle spasms, and numbness and tingling.

Your nerve cells have a protective covering called myelin. Without myelin, the brain and spinal cord can't communicate with the nerves in the rest of your body. MS causes areas in the brain and spinal cord to get inflamed. It slowly damages the myelin and nerves in patches. These patches of damage are called lesions.

MS tends to get worse over time. But usually this happens slowly. It's hard to predict how MS will affect you. MS is different for each person. Some people's lives won't change much when they have MS. They may function well for a long time. But others may lose the ability to walk or do everyday tasks as the disease gets worse.

There is no cure for MS. But medicines and other treatments might help slow its progression and treat your symptoms.

Multiple sclerosis

Multiple sclerosis (MS) is a disease that affects the central nervous system—the brain and spinal cord. It also affects the nerves to the eyes. Your nerve cells have a protective covering called myelin. Without myelin, the brain and spinal cord can't communicate with the nerves in the rest of the body. MS causes areas in the brain and spinal cord to get inflamed. It slowly damages the myelin and nerves in patches. These patches of damage are called lesions.

MS can cause problems with muscle strength, vision, balance, mood, and thinking. It may cause fatigue, pain, muscle spasms, numbness and tingling, and bowel and bladder problems.

MS tends to get worse over time. But this usually happens slowly. There is no cure for MS. But there are medicines and other treatments that might help slow its progression and treat symptoms.

What happens when you have multiple sclerosis (MS)?

The course of MS depends on which type you have. Most people who have MS have attacks over many years. An attack is a period of time when there are new symptoms or when old symptoms get worse. An attack can last for days to weeks. Symptoms usually go away (remit) after an attack. Attacks are also called relapses, flares, or exacerbations.

In general, MS follows one of four courses:

  • Relapsing-remitting. Attacks come and go over time. The disease doesn't get worse between attacks.
  • Secondary progressive. The disease follows a relapsing-remitting course at first. Then it gets worse (progresses) over time, even without attacks.
  • Primary progressive. The disease gets worse from the start, with or without attacks.
  • Clinically isolated syndrome (CIS). This is an MS attack in a person not known to have MS. An MRI only shows damage from this attack. There are not old MS lesions on the MRI. These people may or may not go on to have MS.

It's hard to predict how MS will affect you. Some people may function well for a long time. But others may lose the ability to walk or do everyday tasks as the disease gets worse.

What are the symptoms of multiple sclerosis (MS)?

MS symptoms vary from person to person. They may come and go over time. MS can cause problems with muscle strength, vision, balance, mood, and thinking. It may cause fatigue, pain, muscle spasms, and numbness and tingling. It may also cause bowel and bladder problems. As MS progresses, symptoms may get worse.

How is multiple sclerosis (MS) treated?

Different medicines are used to treat MS. Some may slow its progression and help prevent attacks (relapses). Some treat attacks. Others help treat the symptoms. Other treatments may include physical, occupational, speech, or cognitive therapy to help you function better. Counseling and exercise may also help.

Magnetic resonance imaging (MRI) of multiple sclerosis

A technician prepares to slide a patient into an MRI machine.

People who have multiple sclerosis (MS) have damaged areas, called lesions or plaques, in their brain and spinal cord. These areas can be seen using a magnetic resonance imaging (MRI) machine. It uses a strong magnet and radio waves to show places inside the body. Over time, MS can cause the brain to shrink. This can be seen on an MRI too.

How are medicines used to treat multiple sclerosis (MS)?

There are different types of medicines used to treat MS.

Disease-modifying drugs (DMDs) may:

  • Prevent attacks (relapses).
  • Reduce new lesions in the brain and spinal cord.
  • Reduce or slow down the progression of MS.

    DMDs may be:

    • Injected into a vein (infused) once a month, a few times a year, or yearly.
    • Taken as a pill 1 or 2 times a day.
    • Given to yourself as a shot 1 to 3 times a week.

Damage to the nervous system may occur early in the disease, even while symptoms are still mild. Early treatment with DMDs may help prevent or delay some of this damage.

Talk to your doctor about what DMD is right for you. You and your doctor may consider:

  • The type of your MS.
  • Your concerns about risks and side effects.
  • How well the medicine works.
  • The cost of the medicine.
  • How you prefer to take the medicine (shot, pill, or an IV infusion).
  • If you have attacks or new lesions seen on an MRI.
  • Whether you plan to get pregnant, can become pregnant, can get someone pregnant, or are breastfeeding.

Medicines to treat an attack may:

  • Help you recover faster from an attack.

Medicines that treat ongoing symptoms may:

  • Help with symptoms, such as depression, nerve pain, fatigue, and bladder problems.

How can you care for yourself when you have multiple sclerosis (MS)?

General care

  • Be safe with medicines. Take your medicines exactly as prescribed. Call your doctor if you think you are having a problem with your medicine.
  • Use a cane, walker, or scooter if your doctor suggests it.
  • Keep doing your normal activities as much as you can.
  • Try to stay active mentally. Read or do things like crossword puzzles if you enjoy doing them.
  • Keep cool. For many people, MS symptoms get worse when they are even a little bit hotter. This could be from the weather, a hot shower, exercise, or a fever. Cooling vests, neck wraps, cool cloths, air conditioning and cool showers after exercise can help. So can avoiding hot tubs and saunas.
  • Seek connections. Spend time with friends, family, and others. Joining a support group for people with MS may help.
  • Tell your doctor if you feel sad, depressed, or hopeless. Also tell your doctor if you have lost interest in things you usually enjoy. Medicine and counseling can help.
  • If you smoke, try to quit. Smoking may increase problems caused by MS. If you need help quitting, talk to your doctor about stop-smoking programs and medicines. These can increase your chances of quitting for good.
  • Try to cut down on stress. Calm yourself or release tension by doing an activity you enjoy, such as reading a book, listening to music, or gardening.

Diet and exercise

  • Talk to your doctor about your diet and any supplements you take.
  • Tell your doctor if you're having problems chewing or swallowing. Your doctor or a speech therapist may recommend changes to your diet to help make it easier to swallow. You may need to avoid certain foods or liquids. You also may need to change the thickness of foods or liquids in your diet.
  • If you get full quickly or get tired easily when you eat, try eating smaller meals more often. You can also try a liquid meal replacement such as Ensure or Boost.
  • Get exercise and physical activity on most days. Exercise can be safe even if your symptoms are severe. A physical therapist can help you find the best way to be active. Physical activity and exercise can reduce many of the symptoms of MS. Exercise might also reduce attacks (relapses).
  • Ask your doctor about taking vitamin D. The doctor may suggest taking it and can suggest a dose. Low vitamin D levels may be linked to MS.

What increases your risk for multiple sclerosis (MS)?

Experts don't know why MS happens to some people but not others. The disease runs in families, so there may be a genetic link. MS is more common in people who grew up in regions that are farther away from the equator. Low vitamin D levels may also be linked to MS. Certain infections and smoking may also play a role in MS.

How is complementary and alternative medicine used to treat multiple sclerosis (MS)?

Many complementary and alternative medicine (CAM) treatments have been proposed for people who have MS. Research hasn't shown all of the proposed CAM treatments to be effective or safe for people who have MS. But some treatments may help relieve certain symptoms of MS. For example, some forms of marijuana may help with muscle stiffness (spasticity) and pain.

A person with MS may benefit from safe CAM treatments along with standard medical treatment. For example, some people use acupuncture, massage therapy, mindfulness, or yoga to help with some of their symptoms.

Talk to your doctor if you're interested in trying any of these treatments.

What causes multiple sclerosis (MS)?

The exact cause isn't known, but most experts think that MS is an autoimmune disease. In MS, the immune system attacks the protective covering of the nerve cells (myelin) in parts of the brain and spinal cord. Areas of the brain and spinal cord get inflamed. Over time, the myelin and nerves are damaged.

What is multiple sclerosis (MS)?

Multiple sclerosis (MS) is a disease that affects the central nervous system—the brain and spinal cord. It can cause problems with muscle strength, vision, balance, mood, sensation, and thinking. MS tends to get worse over time. But usually this happens slowly. Medicines and other treatments might help slow its progression and treat symptoms.

What cognitive and mental health problems can be caused by multiple sclerosis (MS)?

MS can cause cognitive problems. These may include trouble with:

  • Memory, especially short-term memory.
  • Problem solving.
  • Keeping attention on a mental task.
  • Finding the right words to express yourself.
  • Grasping ideas quickly.

These problems can occur early in the course of the disease. And they may get worse with time. These problems can also be a side effect of medicines you're taking for other MS symptoms. Or they could be made worse by other symptoms of MS, like depression, fatigue, pain, and sleep problems.

MS can also cause mental health problems. Someone who has MS may:

  • Have depression.
  • Have thoughts of suicide.
  • Have anxiety.
  • Feel sad, worried, or angry.
  • Feel lonely or be isolated.
  • Laugh or cry suddenly for no reason, even if something isn't funny or sad.

Medicines and counseling can help treat problems caused by MS. Joining a support group for people with MS can also be an option. Talk to your doctor if you need help.

People with MS are more likely to die by suicide. Emergency help is available 24 hours a day, 7 days a week. If you or someone you know talks about suicide, self-harm, a mental-health crisis, a substance-use crisis, or any other kind of emotional distress, get help right away. You can:

  • Call the Suicide and Crisis Lifeline at 988.
  • Call 1-800-273-TALK (1-800-273-8255).
  • Text HOME to 741741 to access the Crisis Text Line.

Consider saving these numbers in your phone.

Go to 988lifeline.org for more information or to chat online.

Multiple sclerosis (MS): Modifying your home

If you have trouble moving around or you get tired easily because of MS, it may help to make some changes in your home. Here are some things you can do.

  • Change the location of furniture.

    Arrange furniture so you can hold on to something as you move around the house.

  • Use specially modified chairs.

    They can help make it easier to sit down and stand up.

  • Group the items you use most often.

    Put things like reading glasses, keys, and the telephone in one easy-to-reach place. Then you can avoid having to walk long distances to get them.

  • Tack down or remove rugs to prevent tripping.
  • Put no-slip tape in the bathtub and install grab bars to prevent falls.

An occupational or physical therapist can help you make these and other changes to your home. This includes helping you to find ways to make dressing, bathing, and eating easier. Contact the National Multiple Sclerosis Society for other sources of advice and information on adapting your home environment to meet your changing needs.

Multiple sclerosis (MS): When to call

Call your doctor now or seek immediate medical care if:

  • You think you are having an attack (relapse).
  • You fall or have another injury.
  • You have new vision problems or eye pain.
  • You have symptoms of a urinary infection. For example:
    • You have blood or pus in your urine.
    • You have pain in your back just below your rib cage. This is called flank pain.
    • You have a fever, chills, or body aches.
    • It hurts to urinate.
    • You have groin or belly pain.

Watch closely for changes in your health, and be sure to contact your doctor if:

  • You want more information about MS or medicines.
  • You feel sad or hopeless, or you don't enjoy things like you once did. You may be depressed.
  • You have new or worse symptoms.
  • You are worried about falling.
  • You have questions about alternative treatments. Do not use any other treatments without talking to your doctor first.

How are therapies used to treat multiple sclerosis (MS)?

Therapy is used to help improve specific skills that are lost or damaged due to MS. MS can cause problems with muscle control and strength, vision, and balance. It can also affect your thinking. Your therapy needs may change over time as your symptoms change.

There are many types of therapy that can help you function better when you have MS. They include:

Physical therapy

This therapy uses exercise of all types to help you stay as independent as possible. Your therapist will help you find which exercises are best for you. Exercise and physical activity are good for all people who have MS. And it's still important even as the disease gets worse.

Exercises will:

  • Stretch and strengthen muscles.
  • Get your heart and lungs working harder.
  • Help you with your balance and ability to move.

You'll also learn how to cool off between exercises, since heat can make symptoms worse.

Occupational therapy

This therapy teaches you how to be as independent as possible.

You can learn how to use equipment or aids to help you with your daily life. This includes aids that help you eat, get dressed, bathe, and do other tasks.

You can also learn how to save energy while you do those tasks. And you can learn how to do them while using a cane, a walker, or a wheelchair.

Speech therapy

MS can affect the nerves that help you to talk and swallow. With therapy, you may be able to:

  • Reduce long pauses or slurring.
  • Reduce the nasal sound that can happen when your face muscles get too relaxed.
  • Improve your speech patterns and the way you pronounce words.
  • Learn other ways to communicate, such as with a phone or alphabet cards.
  • Learn what foods and eating habits can help if it's hard to swallow.

Cognitive retraining

"Cognitive" is a word that refers to your brain's ability to do things like remember, solve problems, and make decisions. MS can make these things harder.

Therapy can often retrain your brain to find other ways to do these tasks. For example, you may learn to rely on other ways to remember and stay organized, like using a computer, a cell phone, a notebook, or a filing system.

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The content above contains general health information provided by Healthwise, Incorporated, and reviewed by its medical experts. This content should not replace the advice of your healthcare provider. Not all treatments or services described are offered as services by us. For recommended treatments, please consult your healthcare provider.